Preventing brain diseases


 

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What Causes Alzheimer's Disease? 6 Risk Factors to Know

For many years, doctors have been workingover 85 are said to have developed some
hard to determine what causes Alzheimer'sdegree  of  Alzheimer's.
disease. Due to the complex nature of the
disease, the exact causes are not yet fully2. Family History - Your chances of
understood. However, strides are being madedeveloping Alzheimer's are up to 7 times
on a daily basis, and researchers have a muchgreater if you have a first degree relative
clearer picture of Alzheimer's than they did(parent, sibling) that has the disease. This
even  a  few  years  ago.number is even higher if multiple family
members  have  the  disease.
Most people with Alzheimer's disease have
large quantities of plaques and tangles built3. Genetics - The APOE-e4 gene has been
up in their brain. Plaques are deposits ofidentified as a risk gene for Alzheimer's. A
the protein beta-amyloid accumulating in therisk gene increases the likelihood of
spaces between the brain's nerve cells.developing a disease, but unlike a
Tangles are deposits of the protein tau thatdeterministic gene, it fortunately doesn't
accumulate and become twisted inside of theguarantee  you  will  develop  it.
brain's  nerve  cells
The APOE gene provides the blueprint for one
Two  Types  of  Alzheimer's  Diseaseof the proteins that carries cholesterol in
the blood stream. Everyone inherits a copy of
Researchers have determined that there arean APOE gene from each parent. There are
two types of Alzheimer's: Familialthree types of APOE genes: APOE-e2, APOE-e3,
Alzheimer's disease and Sporadic Alzheimer'sand APOE-e4. Only the APOE-e4 gene has been
disease.linked to Alzheimer's. People with one copy
of the APOE-e4 gene are 2-3 times more likely
Familial Alzheimer's is a rare form of theto develop Alzheimer's. People with two
disease. It is characterized by an earlycopies of the gene (approximately 1% of the
onset and affects less than 10% ofpopulation)  have  a  9  times  greater risk.
Alzheimer's  patients.
4. Gender - Women have a greater risk of
People with Familial Alzheimer's have adeveloping  Alzheimer's  than  men.
"deterministic gene" which inevitably leads
to the development of the disease. Only a few5. Education - Several studies have shown a
hundred families in the world have been foundconnection between less education and an
to carry the deterministic gene forincreased risk of Alzheimer's. However, more
Alzheimer's.research  is  needed  in  this  area.
Sporadic Alzheimer's is the more common form6. Head Injuries - Serious traumatic head
of the disease. There is no deterministicinjuries, such as concussions, have been
gene present in Sporadic Alzheimer'slinked  to  an increased risk of Alzheimer's.
patients. The onset of the disease is much
later  in  life  (usually  after  age  65).But there is good news. According to Dharma
Singh Khalsa, M.D., President and Medical
Although there is no specific gene linked toDirector of the non-profit Alzheimer's
this form of the disease, genetic factors doResearch and Prevention Foundation, many of
appear  to  play  a  role in its development.these risk factors can be controlled by
adopting  good  lifestyle  choices.
6  Risk  Factors  to  Know  Right  Now
Dr. Khalsa has found that by lowering stress,
Doctors have identified several risk factorsmaintaining a healthy diet, and staying
which they can link to the development ofphysically and mentally active, it is
Alzheimer's. The following 6 factors havepossible to dramatically reduce your risk of
shown  to be prominent causes of the disease:developing  Alzheimer's.
1. Age - Alzheimer's disease usually developsSo while we are still uncertain as to
after age 65. Less than 5% of people ageprecisely what causes Alzheimer's disease, it
65-74 have Alzheimer's, but the chance ofis clear that we have considerable power to
developing the disease doubles every 5 yearslower our chances of developing it - if we
after age 65. Almost 50% of the populationtake good care of our body and mind.



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